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Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin |
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| Authors: | Hui Xu Tianbo Li Alexis Rohou Christopher P Arthur Foteini Tzakoniati Evera Wong Alberto Estevez Christine Kugel Yvonne Franke Jun Chen Claudio Ciferri David H Hackos Christopher M Koth Jian Payandeh |
| Institution: | 1. Department of Structural Biology, Genentech, South San Francisco, CA 94080, USA;2. Department of Biochemical and Cellular Pharmacology, Genentech, South San Francisco, CA 94080, USA;3. Department of Neuroscience, Genentech, South San Francisco, CA 94080, USA;4. Department of Biomolecular Resources, Genentech, South San Francisco, CA 94080, USA |
| Abstract: |  |
| Keywords: | voltage-gated sodium channel protoxin II Nav1 7 gating modifier toxin inhibitor cystine knot gating model |
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