|
|||||
|
|
Phomoeuphorbins A-D, azaphilones from the fungus Phomopsis euphorbiae |
|
| Authors: | Yu Bu-Zhu Zhang Gao-Hong Du Zhi-Zhi Zheng Yong-Tang Xu Jian-Chu Luo Xiao-Dong |
| Institution: | a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, PR China b Laboratory of Molecular Immunopharmacology, Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650203, PR China c Graduate School of the Chinese Academy of Science, Beijing 100050, PR China |
| Abstract: | Four azaphilones, named phomoeuphorbins A-D (1-4) were isolated from cultures of Phomopsis euphorbiae, an endophytic fungus isolated from Trewia nudiflora. Structures of 1-4 were established on the basis of spectroscopic analyses, including application of 2D NMR spectroscopic techniques. Phomoeuphorbins A and C exhibited very weak inhibitory activities against HIV replication in C8166 cells in vitro. |
| Keywords: | Phomopsis euphorbiae Trewia nudiflora Euphorbiaceae Azaphilone Phomoeuphorbin Anti-HIV |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |