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Fine genetic mapping of the chromosome 11q23.3 region in a Han Chinese population: insights into the apolipoprotein genes underlying the blood lipid-lipoprotein variances
Affiliation:1. Department of Genetics, Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center at Shanghai and Shanghai Academy of Science and Technology, Shanghai 200025, China;2. Department of Cardiology, Changhai Hospital, The Second Military Medical University, Shanghai 200433, China;1. Jiangsu Key Laboratory of Xenotransplantation, Nanjing Medical University, Nanjing 211166, China;2. Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Nanjing Medical University, Nanjing 211166, China;3. Department of Cell Biology, Guangdong Provincial Key Laboratory of Bone and Joint Degenerative Diseases, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China;4. State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 211166, China;5. Shenzhen Xenotransplantation Medical Engineering Research and Development Center, Institute of Translational Medicine, Shenzhen Second People''s Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen 518035, China;1. Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA;2. Department of Embryology, Carnegie Institution for Science, Baltimore, Maryland, USA;3. Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA;1. Key Laboratory of Reproductive Genetics (Ministry of Education) and Department of Reproductive Endocrinology, Women''s Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310006, China;2. Key Laboratory of Women''s Reproductive Health of Zhejiang Province, Hangzhou, Zhejiang 310006, China;1. Division of Experimental Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA;2. Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA;3. Department of Chemistry and Biochemistry, University of California San Diego, San Diego, CA, USA;4. Analytical Development, Pharmaceutical Sciences, Takeda Pharmaceutical Company, Lexington, MA, USA;5. Finsen Laboratory, Rigshospitalet, Copenhagen, Denmark;6. Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark;7. Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
Abstract:
Keywords:Blood lipids  Coronary artery disease  Genetic associations  Progressive analyses for prioritizing  Causal genetic factors
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