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Comparison of follicular fluid and serum levels of Inhibin A and Inhibin B with calculated indices used as predictive markers of ovarian hyperstimulation syndrome in IVF patients |
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| Authors: | Jiri Moos Karel Rezabek Vanda Filova Martina Moosova Jana Pavelkova and Jana Peknicova |
| Institution: | (1) Assisted Reproduction Centre, Department of Obstetrics and Gynecology, General Teaching Hospital in Prague, Prague, Czech Republic;(2) Sigma-Aldrich spol. s r.o., Prague, Czech Republic;(3) Immunotech a.s., Prague, Czech Republic;(4) Laboratory of Diagnostics for Reproductive Medicine, Institute of Biotechnology, Academy of Sciences of the Czech Republic v. v. i., Prague, Czech Republic |
| Abstract: | BackgroundOvarian Hyperstimulation Syndrome (OHSS) is a severe health complication observed in some patients undergoing hormonal stimulation during IVF. Presence of OHSS is often associated with a high count of growing follicles responding to FSH hyperstimulation. However, the number of responding follicles may not be sufficient enough to predict the onset and severity of OHSS. The aim of this study was to find whether follicular fluid (FF) and serum concentrations of Inhibin A and Inhibin B in patients undergoing IVF treatment may serve as a predictor of OHSS status independent of the growing follicles count. |
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