Brain Pericytes: Emerging Concepts and Functional Roles in Brain Homeostasis |
| |
Authors: | Masahiro Kamouchi Tetsuro Ago Takanari Kitazono |
| |
Institution: | (1) Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku Fukuoka, 812-8582, Japan |
| |
Abstract: | Brain pericytes are an important constituent of neurovascular unit. They encircle endothelial cells and contribute to the
maturation and stabilization of the capillaries in the brain. Recent studies have revealed that brain pericytes play pivotal
roles in a variety of brain functions, such as regulation of capillary flow, angiogenesis, blood brain barrier, immune responses,
and hemostasis. In addition, brain pericytes are pluripotent and can differentiate into different lineages similar to mesenchymal
stem cells. The brain pericytes are revisited as a key player to maintain brain function and repair brain damage. |
| |
Keywords: | |
本文献已被 PubMed SpringerLink 等数据库收录! |
|