Molecular functions of small regulatory noncoding RNA |
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Authors: | Yong Huang Ji Liang Zhang Xue Li Yu Ting Sheng Xu Zhan Bin Wang Xiang Chao Cheng |
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Institution: | 19723. Animal Science and Technology College, He Nan University of Science and Technology, Luoyang City, 471003, Henan Province, PR China
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Abstract: | Recently, using large-scale genomic sequencing, a great number of small noncoding RNAs (ncRNA) has been discovered. Short ncRNAs can be classified into three major classes — small interfering RNA (siRNA), microRNA (miRNA), and piwi-interacting RNA (piRNA). These short ncRNAs ranging from 20 to 300 nt in size are now recognized as a new paradigm of gene regulation for controlling many biological processes. In this paper, we review the biogenesis and recent research on the functions of small regulatory non-coding RNAs and aim at understanding their important functions in living organisms. |
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