Localization of factors controlling spermatogenesis in the nonfluorescent portion of the human y chromosome long arm |
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Authors: | L Tiepolo Orsetta Zuffardi |
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Affiliation: | (1) Institute of General Biology, Medical Faculty, University of Pavia, Italy;(2) c/o Gruppo Euratom, Via Forlanini, 14, I-27 100 Pavia, Italy |
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Abstract: | Summary A deletion of the Y chromosome at the distal portion of band q11 was found in 6 men with normal male habitus but with azoospermia. Five of them were found during a survey of 1170 subfertile males while the sixth was karyotyped because of slight bone abnormalities. These findings, together with a review of the literature, suggest that on the distal portion of the nonfluorescent segment of the long arm of the Y, factors are located controlling spermatogenesis. |
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