YA is needed for proper nuclear organization to transition between meiosis and mitosis in Drosophila |
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Authors: | Katharine L Sackton Jacqueline M Lopez Cindy L Berman Mariana F Wolfner |
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Affiliation: | (1) Dept of Molecular Biology and Genetics, Cornell University, 14853 Ithaca, NY, USA |
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Abstract: | Background The Drosophila YA protein is required to initiate the embryonic cleavage divisions. After egg activation, YA enters nuclei and interacts with chromatin and the nuclear lamina. This study was designed to define more precisely the events prior to the first cleavage division that are dependent upon YA. |
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