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The Values of Combined and Sub-Stratified Imaging Scores with Ultrasonography and Mammography in Breast Cancer Subtypes
Authors:Tsun-Hou Chang  Hsian-He Hsu  Yu-Ching Chou  Jyh-Cherng Yu  Giu-Cheng Hsu  Guo-Shu Huang  Guo-Shiou Liao
Affiliation:1. Department of Radiology, Tri-Services General Hospital, Taipei, Taiwan.; 2. Department of Radiology, National Defense Medical Center, Taipei, Taiwan.; 3. School of Public Health, National Defense Medical Center, Taipei, Taiwan.; 4. Division of General Surgery, Department of Surgery, Tri-Services General Hospital, National Defense Medical Center, Taipei, Taiwan.; 5. Breast Medical Center, Kang-Ning General Hospital, Taipei, Taiwan.; School of Medicine, Fu Jen Catholic University, TAIWAN,
Abstract:ResultsThese selected cases were evaluated by the “5-point score.” MG, US, and combined and sub-stratified imaging assessments all revealed statistically significant (P < 0.001) incidence of malignancy. The sensitivity was increased in the combined imaging score (99.8%), and the specificity was increased in the sub-stratified combined score (75.4%). In the sub-stratified combined imaging assessment, all BCS can be classified with higher scores (abnormality hierarchy), and luminal B subtype showed the most salient result (hierarchy: higher, 95%; lower, 5%).ConclusionsCombined and sub-stratified imaging assessments can increase sensitivity and specificity of breast cancer diagnosis, respectively, and Luminal B subtype shows the best identification by sub-stratified combined imaging scoring.
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