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Sequences upstream and downstream from the glutamine-dependent carbamoyl phosphate synthetase-encoding gene from the protozoan Babesia bovis
Affiliation:1. Michigan Technological University (MTU), Hougton, MI USA 49931;2. Plastics Packaging and Consumer Products, American Chemistry Council (ACC), Washington, DC USA 20002;3. Idaho National Laboratory (INL), Idaho Falls, ID USA 83415;1. Department of Cardiology, West China Hospital of Sichuan University, Chengdu, China;2. Department of Cardiology, Maternal and Child Health Hospital, Longquanyi District, Chengdu, China;3. Department of Cardiology, Hospital of Traditional Chinese Medicine, Shuangliu District, Chengdu, China;4. Department of Cardiovascular Medicine, Hospital of Chengdu Office of People''s Government of Tibetan Autonomous Region, Chengdu, China;5. Department of Cardiology, First People''s Hospital, Longquanyi District, Chengdu, China
Abstract:In the protozoan parasite, Babesia bovis, the glutamine-dependent carbamoyl phosphate synthetase-encoding gene (CPSII) contains contiguous amidotransferase- and synthetase-encoding sequences. Unlike the organisation in most eukaryotes, the gene is not fused with other genes encoding enzymes of pyrimidine biosynthesis de novo. The nucleotide sequences immediately upstream and downstream from the gene contain motifs which may be involved in regulating its expression.
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