TERT over-expression affects the growth of myocardial tissue derived from mouse embryonic stem cells

For heart failure, new therapeutic strategies based on augmentation of the regenerative resources of the heart muscle are under evaluation. More knowledge about the mechanisms regulating growth of the embryonic or adult heart muscle will help to improve the results. The present over-expression study provides further insight into the role of telomerase reverse transcriptase (TERT) in growth regulation of myocardial tissue derived from embryonic stem (ES) cells.