| 毕赤酵母高密度发酵研究进展 |
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| 引用本文： | 李洪淼,王红宁,许钦坤. 毕赤酵母高密度发酵研究进展[J]. 生物技术通讯, 2005, 16(2): 210-212 |
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| 作者姓名： | 李洪淼 王红宁 许钦坤 |
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| 作者单位： | 四川农业大学,动物科技学院,四川,雅安,625014 |
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| 基金项目： | 国家“十五”重点科技攻关子课题(2002BA514A-12) |
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| 摘 要： | 巴斯德毕赤酵母表达系统是近年发展起来的一种优秀的真核表达系统.本从培养基、温度、pH值、溶氧、甲醇的流加等角度对国内外毕赤酵母高密度发酵的研究进展做了较详细的综述,并提出了目前毕赤酵母高密度发酵过程中存在的问题.
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| 关 键 词： | 毕赤酵母 高密度发酵 生物学特性 发酵工艺 外源蛋白 真核表达系统 |
| 文章编号： | 1009-0002(2005)02-0210-03 |
| 修稿时间： | 2004-09-10 |
Advancce of Pichia pastoris on High-density Fermentation |
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| LI Hong-miao,WANG Hong-ning,XU Qin-kun. Advancce of Pichia pastoris on High-density Fermentation[J]. Letters in Biotechnology, 2005, 16(2): 210-212 |
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| Authors: | LI Hong-miao WANG Hong-ning XU Qin-kun |
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| Affiliation: | LI Hong-miao,WANG Hong-ning,XU Qin-kunCollege of Animal Science and Technology,Sichuan Agricultural University,Ya'an 625014,China |
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| Abstract: | Pichia pastoris has been utilized widely as an excellent heterologous gene expression system recently. In this paper, the basic research and recent advances of Pichia pastoris on high-density fermention were reviewd, and the focuses on culture medium, temperature, pH, dissolved oxygen, methanol, were described and discussed. |
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| Keywords: | Pichia pastoris high-density fermentation |
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