| 简述疫苗研发动物模型 |
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| 引用本文： | 吴浩飞,任富利(综述),胡秀兰,杨晓明(审校). 简述疫苗研发动物模型[J]. 微生物学免疫学进展, 2014, 0(5): 81-85 |
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| 作者姓名： | 吴浩飞 任富利(综述) 胡秀兰 杨晓明(审校) |
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| 作者单位： | 武汉生物制品研究所有限责任公司,湖北武汉,430207 |
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| 摘 要： | 在过去的100年里,动物模型的研究已在人类疫苗的发展中起到至关重要的作用。动物模型的使用不仅有助于疫苗从基本研究转到临床应用,而且动物模型通常能够预测疫苗实用的潜能,从而帮助疫苗的生产商预测财政风险。由于每种动物模型都有其自身的优缺点,选择一种合适的动物模型可促进疫苗研发的顺利进行。
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| 关 键 词： | 动物模型 疫苗研发 临床应用 |
Introduction of animal models in development of vaccines |
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| WU Hao-fei,REN Fu-li,HU Xiu-lan,YANG Xiao-ming. Introduction of animal models in development of vaccines[J]. Progress In Microbiology and Immunology, 2014, 0(5): 81-85 |
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| Authors: | WU Hao-fei REN Fu-li HU Xiu-lan YANG Xiao-ming |
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| Affiliation: | WU Hao-fei, REN Fu-li, HU Xiu-lan, YANG Xiao-ming( Research and Development Department. Wuhan Institute of Biological Products Co. , Ltd. , Wuhan 430207, Hubei Province, China) |
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| Abstract: | In the past 100 years, the animal models have played a crucial role in the development of human vaccines .Ani-mal models help to make the translation from basic research to clinical application , and they often allow prediction of the vaccine potential in application , which helps in predicting the financial risks for vaccine manufacturers .Since each animal model has its own advantages and disadvantages , choosing a suitable animal model could promote the research and develop-ment process of vaccine . |
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| Keywords: | Animal models Vaccine development Clinical application |
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