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Identification and characterization of CMP-NeuAc:GalNAc-IgA1 alpha2,6-sialyltransferase in IgA1-producing cells
Authors:Raska Milan  Moldoveanu Zina  Suzuki Hitoshi  Brown Rhubell  Kulhavy Rose  Andrasi Judit  Hall Stacy  Vu Huong L  Carlsson Fredric  Lindahl Gunnar  Tomana Milan  Julian Bruce A  Wyatt Robert J  Mestecky Jiri  Novak Jan
Affiliation:University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Abstract:
Keywords:C1β3GalT1, core 1 β1,3-galactosyltransferase   Cosmc, C1β3GalT1-specific molecular chaperone   C3, third component of complement cascade   CMP-Neu5Ac, CMP-5 N-acetylneuraminic acid   DPBS, Dulbecco’s phosphate buffered saline   EBV, Epstein-Barr virus   GalNAc, N-acetylgalactosamine   GalT, β1,3-galactosyltransferase   HAA, Helix aspersa agglutinin   HSPN, Henoch-Schoenlein purpura nephritis   IgAN, IgA nephropathy   NeuAc, N-acetyl neuraminic acid   PBMC, peripheral blood mononuclear cells   PNA, peanut agglutinin   PWM, pokeweed mitogen   SA, sialic acid   ST6-GalNAcI, (SIAT7A)   ST6-GalNAcII, (SIAT7B)   ST6-GalNAcIV, (SIAT7D)   ST6-GalNAcVI, (ST6-GalNAcF)   CMP-NeuAc-R-GalNAc-α1-O-Ser/Thr α2,6-sialyltransferases I, II, IV, and VI
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