Continuum remodeling revisited |
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Authors: | Charles H Negus Thomas J Impelluso |
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Institution: | (1) Department of Mechanical and Aerospace Engineering, University of California, 9500 Gilman Drive, San Diego La Jolla, CA 92093-0411, USA;(2) Department of Mechanical Engineering, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182-1323, USA;(3) Present address: L-3 Jaycor Simulation, Engineering and Testing, 3394 Carmel Mountain Road, San Diego, CA 92121-1002, USA |
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Abstract: | Recent research effort in bone remodeling has been directed toward describing interstitial fluid flow in the lacuno-canalicular
system and its potential as a cellular stimulus. Regardless of the precise contents of the mechanotransduction “black box”,
it seems clear that the fluid flow on which the remodeling is predicated cannot occur under static loading conditions. In
an attempt to help continuum remodeling simulations catch up with cellular and subcellular research, this paper presents a
simple, strain rate driven remodeling algorithm for density allocation and principal material direction rotations. An explicit
finite element code was written and deployed on a supercomputer which discretizes the remodeling process and uses an objective
hypoelastic constitutive law to simulate trabecular realignment. Results indicate that a target strain rate for this dynamic
approach is |D
I
*| = 1.7% per second which seems reasonable when compared to observed strain rates. Simulations indicate that a morpho-mechanically
realistic three-dimensional bone can be synthesized by applying a few dynamic loads at the envelope of common daily physiological
rates, even with no static loading component. |
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Keywords: | Bone remodeling Dynamic stimulus Hypoelastic Three-dimensional Finite element analysis Cyberinfrastructure |
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