Continuous production of poly(3-hydroxybutyrate-co-3-hyhroxyvalerate) byAlcaligenes eutrophus |
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| Authors: | Naoyuki Koyama Yoshiharu Doi |
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| Institution: | (1) Polymer Chemistry Laboratory, The Institute of Physical and Chemical Research (RIKEN), Hirosawa, Wako-shi, 351-01 Saitama, Japan |
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| Abstract: | Summary Copolymers of 3-hydroxybutyrate (3HB) and 3-hydroxyvalerate (3HV) were produced in a continuous culture ofAlcaligenes eutrophus with 17.5 gl
–1 of fructose and 2.5gl
–1 of pentanoic acid in the feed. The P(3HB-co-3HV) productivity was maximal at a dilution rate of 0.17h–1 and yielded 0.31gl
–1h–1 under an ammonium-limited condition. The 3HV content in copolymers increased from 11 to 79 mol% as the dilution rate of cells was increased from 0.06 to 0.32h–1. |
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