Evidence for the gamma-glutamyl cycle in yeast. |
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Authors: | E D Mooz L Wigglesworth |
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Institution: | Department of Chemistry, Bowdoin College Brunswick, Maine 04011 USA |
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Abstract: | Many previous studies have shown that yeast contains high concentrations of glutathione and enzymes needed for its synthesis. We report here that yeast also contains γ-glutamyl transpeptidase, γ-glutamyl cyclotransferase, dipeptidase, and 5-oxoprolinase activities, suggesting that the γ-glutamyl cycle may be operative in yeast. The presence of the cycle enzymes in yeast offers a simple free-cell system which can probably be adapted to studies on the function of this cycle. |
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