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胃幽门螺杆菌感染与口臭的相关性研究
引用本文:龚宇华,潘炜娟,魏本娟,郁利,虢灿杰.胃幽门螺杆菌感染与口臭的相关性研究[J].现代生物医学进展,2015,15(1):66-68.
作者姓名:龚宇华  潘炜娟  魏本娟  郁利  虢灿杰
作者单位:上海交通大学医学院附属仁济医院口腔科;上海交通大学医学院附属仁济医院消化所及消化科
基金项目:国家自然科学基金青年科学基金项目(81100296)
摘    要:目的:探讨胃幽门螺杆菌感染与口臭发生的相关性。方法:选取48例口臭患者为研究对象,另选取96例无口臭的健康志愿者为无口臭组,通过13C呼气试验检测所有研究对象幽门螺杆菌的感染情况,比较两组幽门螺杆菌的感染率。根据是否感染幽门螺杆菌分为感染组和无感染组,比较两组口臭的发生率,分析幽门螺杆菌感染与口臭发生的相关性。结果:口臭组和非口臭组患者幽门螺杆菌的感染率分别为79.17%,27.08%,口臭组显著高于无口臭组,差异有统计学意义(x2=35.16,P0.05)。口臭与幽门螺杆菌的感染显著相关(r=0.4)。幽门螺杆菌感染组患者和未感染组口臭的发生率分别为70.31%和3.75%,感染组显著高于未感染组,差异有统计学意义(x2=70.89,P0.05)。幽门螺杆菌的感染与口臭的发生率显著相关(r=0.69)。结论:幽门螺杆菌感染与口臭的发生有密切的相关性,是引起口臭的一个重要因素。

关 键 词:口臭  幽门螺杆菌  相关性

The Correlative Research of Gastric Helicobacter Pylori Infection with Bromopnea
Institution:GONG Yu-hua;PAN Wei-juan;WEI Ben-juan;YU Li;GOU Can-jie;Department of Stomatology, Ren Ji Hospital, School of medicine, Shanghai Jiao Tong University;Digestive Disease Laboratory and Department of Gastroenterology, Ren Ji Hospital, School of medicine, Shanghai Jiao Tong University;
Abstract:Objective:To discuss the correlation of gastric Helicobacter Pylori infection with bromopnea.Methods:48 cases of patients with bromopnea were selected as the research object of bromopnea group, and the other 96 cases of healthy volunteers without bromopnea were selected as non bromopnea group. The Helicobacter Pylori infection rate of two groups were compared by 13C-UBT. Then all research objects were divided into the infection group and non-infection group according to the infection, and the bromopnea occurrence rate of two groups were compared. The correlation of infection with bromopnea occurrence was analyzed.Results:The Helicobacter Pylori infection rate of bromopnea group was 79.17%, which was 27.08% in non bromopnea group and was significantly lower than the bromopnea group (x2=35.16, P<0.05). The correlation coefficient of bromopnea and helicobacter pylori infection rates was 0.49. The bromopnea occurrence rate of infection group was 70.31%, which was 3.75%in the non-infection group and significantly lower than infection group (x2=70.89, P<0.05). The correlation coefficient of bromopnea and Helicobacter Pylori infection rates was 0.69.Conclusion:The Helicobacter Pylori infection had closely correlation with bromopnea, and was one of the important factors of bromopnea.
Keywords:Bromopnea  Helicobacter pylori  Correlation
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