Isolation and characterization of fatty acid binding protein in the liver of the nurse shark, Ginglymostoma cirratum. |
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| Authors: | N M Bass J A Manning C A Luer |
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| Institution: | Department of Medicine, Liver Center, University of California, San Francisco 94143. |
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| Abstract: | 1. A 14.5 kDa fatty acid binding protein was isolated from the liver of the nurse shark, Ginglymostoma cirratum. 2. Purified shark liver FABP (pI = 5.4) bound oleic acid at a single site with an affinity similar to that of mammalian FABP. 3. The apparent size, pI and amino acid composition of shark liver FABP indicate a close structural relationship between this protein and mammalian heart FABP. |
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