The binding of progesterone in different parts of the rabbit uterus during implantation |
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Authors: | Raj K Puri S K Roy |
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Institution: | (1) Division of Endocrinology, Central Drug Research Institute, 226 001 Lucknow |
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Abstract: | Progesterone receptors, both nuclear and cytosolic, were determined in the embryonic and inter-embryonic segments of the rabbit
uterus at 6, 7 and 8 daypost-coitum. At day6 postcoitum a higher concentration of nuclear receptor in the embryonic segment was observed compared with that in the inter-embryonic
segment. A reverse situation was observed in the case of cytoplasmic receptors. On the 7th daypost-coitum, no significant alteration in the concentration of either kind of the receptors was observed. However, on day 8, a higher
concentration of both nuclear and cytosolic receptors at the embryonic site was observed compared to that in inter-embryonic
segment. Since receptors are influenced only in the immediate vicinity of the blastocyst, it can be suggested that the blastocyst
plays a role in the induction of its own implantation. Further, at day 8 increase in receptor concentration at the embryonic
site may be related to the presence of decidual tissue at this site.
CDRI Communication no. 2741. |
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Keywords: | Rabbit uterus progesterone receptors |
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