| 阿扎霉素B产生菌吸水链霉菌NND—52的诱变筛选 |
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| 引用本文： | 王世梅,黄为一,等.阿扎霉素B产生菌吸水链霉菌NND—52的诱变筛选[J].微生物学通报,2001,28(1):64-67. |
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| 作者姓名： | 王世梅 黄为一 |
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| 作者单位： | 南京农业大学微生物学系，南京210095 |
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| 基金项目： | 高等学校博士点基金资助项目 |
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| 摘 要： | 用紫外线，紫外线加氯化锂（LiCl)、吖啶橙3种诱变方式对阿扎霉素（Azalomycin)B产生菌Strepto-myces hygroscopicus NND-52菌株进行诱变处理，确定了它们的最佳诱变剂量，获得了数株Azalomycin B产量较出发菌株提高3倍以上的高产菌株，编号Al3的菌株摇瓶产量达1100mg/L，且传代稳定。经过对3种诱变方式的比校，发现后两种诱变方式对产量的提高更为有效。
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| 关 键 词： | 吸水链霉菌 诱变 阿扎霉素B 抗生素 放线菌 |
| 文章编号： | 0253-2654(2001)01-064-05 |
| 修稿时间： | 1999年8月20日 |
MUTAGENESIS OF STREPTOMYCES HYGROSCOPICUS
NND-52 PRODUCING AZALOMYCIN B |
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| WANG Shi,Mei,HUANG Wei,Yi,CUI Feng,Yuan.MUTAGENESIS OF STREPTOMYCES HYGROSCOPICUS
NND-52 PRODUCING AZALOMYCIN B[J].Microbiology,2001,28(1):64-67. |
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| Authors: | WANG Shi Mei HUANG Wei Yi CUI Feng Yuan |
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| Abstract: | Streptomyces hygroscopicus NND 52 producing Azalomycin B was treated with UV,UV LiCl,acridine orange,the best treatment dose was determined. The yields of several strains which were obtained were more than three times thaat ofCK, and the yield of strain A13 was 1100mg/L,they were stable.Through comparing the treating methods, it was shown that the later two methods were more effective |
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| Keywords: | Streptomyces hygroscopicus NND-52 Mutagenesis Azalomycin B |
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