Production of yeast killer toxin in experimentally infected animals |
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| Authors: | Luciano Polonelli Stefania Conti Mara Gerloni Lauresa Campani Massimo Pettoello Mantovani Giulia Morace |
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| Affiliation: | (1) Istituto di Microbiologia, Università degli Studi di Parma, V. le A. Gramsci 14, 43100 Parma, Italy;(2) Dipartimento di Pediatria, Università degli Studi di Napoli, Naples, Italy;(3) Istituto di Microbiologia, Università Cattolica del Sacro Cuore, Largo F. Vito 1, 00168 Rome, Italy |
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| Abstract: | The ability of a killer yeast (Pichia anomala, UCSC 25F) to produce toxin in vivo was demonstrated, for the first time, in tissues of normal and immunosuppressed experimentally infected mice by means of a fluorescent antibody technique and a killer toxin specific monoclonal antibody. The possible significance of the findings is discussed. |
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| Keywords: | Killer toxin production |
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