Neomycin in urinary tract infections; a clinical evaluation

Neomycin was effective in treating 31 cases of severe Gram-negative bacillary urinary tract infections sensitive to neomycin and resistant to other agents. The recommended dosage schedule of 0.5 gm. every 12 hours for five days was demonstrated to be relatively safe. However, close watch should be maintained for signs of nephrotoxicity and ototoxicity.