Molecular Genetics of Alcohol Dependence and Related Endophenotypes |
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| Authors: | Yann Le Strat Nicolas Ramoz Gunter Schumann and Philip Gorwood |
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| Institution: | 1.INSERM U675, IFR02, Université Paris 7, 16 Rue Henri Huchard, 75018 Paris, France;2.Section of Addiction Biology, Institute of Psychiatry, Kings College, De Crespigny Park, London SE5 8AZ, England ;3.AP-HP, Service de Psychiatrie, Hôpital Louis Mourier, 178 Rue des Renouillers, 92700 Colombes, France |
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| Abstract: | Alcohol dependence is a worldwide public health problem, and involves both environmental and genetic vulnerability factors. The heritability of alcohol dependence is rather high, ranging between 50% and 60%, although alcohol dependence is a polygenic, complex disorder. |
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