Resorption of elastic fibers in monkey gingival connective tissue: ultrastructural and immunocytochemical evidence |
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Authors: | Takashi Sawada |
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Institution: | (1) Department of Ultrastructural Science, Tokyo Dental College, Masago 1-2-2, Mihama-ku, Chiba City 261-8502, Japan |
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Abstract: | Little is known about the remodeling of elastic fibers in gingival connective tissue. In this study, elastic fibers in the
lamina propria of monkey gingiva were examined by transmission electron microscopy and immunocytochemistry. Some elastic fibers
were localized at invagination on the surface of the narrow processes of fibroblasts distributed among dense assemblies of
collagen fibrils, and also within coated pits, which were pinching off as coated vesicles. At a higher magnification, the
coated vesicles contained filamentous structures, as well as pentagonal structures similar those previously reported in elastic
fibers. Immunoelectron microscopy demonstrated positive staining for fibrillin, one of the main components of microfibril,
localized either in the coated pits or vesicles. These observations indicate that at least some elastic fibers were resorbed
by fibroblasts, and that, in spite of the general belief that little remodeling of elastic fibers occurs under normal conditions,
resorption of elastic fibers does occur in monkey gingival connective tissue. The functional significance of this is not yet
clear, but it may be involved in facilitating the delicate and efficient adaptation of tissue to physical requirements during
mastication. |
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