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Synthetic riboswitches that induce gene expression in diverse bacterial species |
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| Authors: | Topp Shana Reynoso Colleen M K Seeliger Jessica C Goldlust Ian S Desai Shawn K Murat Dorothée Shen Aimee Puri Aaron W Komeili Arash Bertozzi Carolyn R Scott June R Gallivan Justin P |
| Institution: | Department of Chemistry, Center for Fundamental and Applied Molecular Evolution, Emory University, Atlanta, GA 30322, USA. |
| Abstract: | We developed a series of ligand-inducible riboswitches that control gene expression in diverse species of Gram-negative and Gram-positive bacteria, including human pathogens that have few or no previously reported inducible expression systems. We anticipate that these riboswitches will be useful tools for genetic studies in a wide range of bacteria. |
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