Simple synthesis of climacostol, a defensive secretion by the ciliate Climacostomum virens. |
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| Authors: | Y Abe K Mori |
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| Affiliation: | Department of Mathematics and Science Education, Graduate School of Science, Science University of Tokyo, Japan. |
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| Abstract: | Climacostol [1,3-dihydroxy-5-[(Z)-2'-nonenyl]benzene, 1], a defensive secretion by the protozoan ciliate Climacostomum virens against predators, was synthesized in a 43% overall yield in three steps by starting from methyl 1,3-bis(tert-butyldimethylsilyloxy) phenylacetate (3). |
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