Antimicrobial and other oligopeptides of grapes |
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Authors: | A A Zamyatnin O L Voronina |
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Institution: | 1.Departamento de Informatica, El Centro Cientifico Tecnologico de Valparaiso,Universidad Tecnica Federico Santa Maria,Valparaiso,Chile;2.Bach Institute of Biochemistry,Russian Academy of Sciences,Moscow,Russia |
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Abstract: | Structures and functions of about 700 oligopeptides of various plants are presently known. However, only one polypeptide has
been isolated from grapes and characterized. At the same time, tens of thousands of uncharacterized amino acid sequences have
been revealed in this plant, among which there can also be precursors of oligopeptide regulators. Due to the scientific and
practical importance of innate immunity of agricultural plants, we have undertaken structural and functional investigation
of these sequences to identify new regulatory oligopeptides including antimicrobial agents. For this purpose, we elaborated
a special method of computer analysis enabling comparison of primary structures of putative precursors of grape oligopeptides
with amino acid sequences of known oligopeptides of other plants. Structural similarity served as the basis for prediction
of potential functional properties. As a result, over 20 new structures of antimicrobial and other grape oligopeptides have
been found. |
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