Purification and some properties of low-molecular-weight proteins of Aspidelaps scutatus (shield or shield-nose snake) venom |
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| Authors: | F J Joubert |
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| Affiliation: | National Chemical Research Laboratory, Council for Scientific and Industrial Research, Pretoria, Republic of South Africa. |
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| Abstract: | 1. Fourteen low-molecular-weight proteins from Aspidelaps scutatus venom were purified by gel filtration and ion exchange chromatography. 2. The proteins (toxins) have i.v. LD50 values ranging from 0.12 to 54 micrograms/g mouse. 3. The amino-terminal sequences of the proteins show that 12 of the 14 proteins were pure. 4. The proteins were preliminarily assigned as phospholipases A2, long neurotoxins and cytotoxin homologues. |
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