| 含酚基化合物抑制TBAS生成体系的抗氧化活性比较 |
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| 引用本文： | 张尔贤,俞丽君,陈展科,肖湘.含酚基化合物抑制TBAS生成体系的抗氧化活性比较[J].中国生物化学与分子生物学报,1996,12(3):374-376. |
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| 作者姓名： | 张尔贤 俞丽君 陈展科 肖湘 |
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| 作者单位： | 汕头大学理学院生物学系 |
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| 摘 要： | 含酚基化合物抑制ＴＢＡＳ生成体系的抗氧化活性比较张尔贤，俞丽君，陈展科，肖湘（汕头大学理学院生物学系，汕头５１５０６３）Ｈａｌｌｉｗｅｌｌ（１９８５）［１，２］设计了以２－脱氧－Ｄ－核糖（以下简称脱氧核糖）作为·ＯＨ自由基分子探针的反应系统，通过检测...
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| 收稿时间： | 1996-06-20 |
The Study on Evaluation of the Antioxidative Activity by Using the Inhibition Rate of TBAS Formation as an Indicator |
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| Zhang Er-Xian,Yu Li-Jun,Chen Zhan-Ke,Xiao Xiang.The Study on Evaluation of the Antioxidative Activity by Using the Inhibition Rate of TBAS Formation as an Indicator[J].Chinese Journal of Biochemistry and Molecular Biology,1996,12(3):374-376. |
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| Authors: | Zhang Er-Xian Yu Li-Jun Chen Zhan-Ke Xiao Xiang |
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| Institution: | (Department of Biology, Shanton University, Shantou 515063 |
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| Abstract: | Deoxyribose was found to be damaged and then changed into thiobarbiturate reactive substances(TBAS)by active oxygen species from systems of Fe￣(2+)-hypoxanthin-xanthineoxidase. The results indicated that in Fe￣(2+)-X-XO concentrations system the TBAS production was increased when both deoxyribase and Fe￣(2+) concentrations were increased but similar result with increase of XO was observed only within the 0. 018 U/ml range.This system was applied to determine the activity of scavenge hydroxyl radical of compound containing phenolic group with strong inhibition activity on the formation of TBAS which increases with the increase of its number of phenolic group. |
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| Keywords: | Thiobarturate reactive substances (TBAS) Deoxyribose Phenolic group Hydroxyl radical Antioxidative activity |
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