| Abstract: | Collisions between two lamellar processes extended from a single locomoting cultured cell were examined by time-lapse cinemicrography and transmission electron microscopy. In most cases after contact the forward movement of either one or both of the lamellae ceased and was followed by a phase of retraction of the lamellae resulting in the breaking of the contact. The events correspond well to the contact inhibition of movement expressed when two cells collide. The similarity is also shown in the ultrastructure of the cell contacts which exhibit a close parallel arrangement of the apposed cell membranes and an alignment of microfilaments in the regions of the cytoplasm at the contacts. |
