Diagnostic and therapeutic applications of antiplatelet monoclonal antibodies |
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| Authors: | B S Coller |
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| Affiliation: | Division of Hematology, State University of New York, Stony Brook 11794. |
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| Abstract: | The interaction of platelets with natural and artificial surfaces is briefly reviewed, emphasizing the role of the platelet glycoprotein Ib and IIb/IIIa receptors. Studies utilizing monoclonal antibodies to these receptors for the diagnosis and therapy of hemorrhagic and thrombotic disorders are described, indicating the potential of such agents as platelet inhibitors. |
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