The MUC5AC gene: RFLP analysis with the Jer58 probe |
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| Authors: | P. Pigny W. S. Pratt A. Laine A. Leclercq D. M. Swallow V. C. Nguyen J. P. Aubert N. Porchet |
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| Affiliation: | (1) Biologie et physiopathologie des cellules mucipares, U377 INSERM, Place de Verdun, F-59045 Lille Cedex, France;(2) Laboratoire de cytogénétique et génétique oncologiques, URA 1158 CNRS, Institut Gustave Roussy, F-94805 Villejuif Cedex, France;(3) MRC Human Biochemical Genetics Unit, University College, NW1 2HE London, UK;(4) Laboratoire de Biochimie, USN A et Hôpital Huriez, CHRU de Lille, F-59037 Lille Cedex, France |
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| Abstract: | We have recently obtained evidence that the locus corresponding to three groups of partial tracheobronchial cDNAs (A=Jer47, B=Jer57, C=Jer58) which mapped to chromosome 11p15 and was given the symbol MUC5 corresponds to two distinct genes which we have provisionally called MUC5B and MUC5AC. Here we describe the detection, using the Jer58 probe, which contains a 24-bp tandem repeat, of polymorphism in the MUC5AC gene with seven different restriction enzymes. |
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