胃底腺息肉与胃增生性息肉的临床、内镜特征分析

目的:分析胃底腺息肉与胃增生性息肉的临床、内镜下等特点。方法:回顾性搜集胃镜检出的经病理证实的胃底腺息肉和胃增生性息肉393例纳入分析,按年龄、性别、发生部位、大小、幽门螺杆菌(helicobacter pylori)感染状态、是否使用质子泵抑制剂(proton pump inhibitor)等因素进行分析比较。结果:393例增生性息肉与胃底腺息肉中,男178例,女215例,男女比例为1:1.2,年龄28~89岁。随着年龄的增高,胃息肉发生率越高,但各年龄段分布差异无统计学意义(P>0.05)。不同部位的增生性息肉与胃底腺性息肉大小相比差异有统计学意义(P<0.05)。两种胃息肉的性别分布差异有统计学意义(P<0.05)。增生性息肉H.pylori感染率较胃底腺性息肉高(P<0.05),而胃底腺息肉质子泵抑制剂使用率较胃增生性息肉高(P<0.05)。结论:增生性息肉与幽门螺旋杆菌感染有关,胃底腺息肉与质子泵抑制剂使用有关。对胃底腺息肉与胃增生性息肉的临床、内镜特点的分析有助于胃镜检查对胃息肉性质的初步判断,提高诊断的准确性。

Clinical and Endoscopic Analysis of Gastric Fundus Polyps and Gastric Hyperplastic Polyps

ABSTRACT Objective: To analyze the clinical and endoscopic features of gastric fundus polyps and gastric hyperplastic polyps. Methods: A retrospective collection of 393 cases of pathologically confirmed fundus glandular polyps and gastric hyperplastic polyps detected by gastroscopy was included in the analysis according to age, sex, location, size, Helicobacter pylori infection status, proton use. Factors such as pump inhibitor (proton pump inhibitor) were analyzed and compared. Results: Of the 393 hyperplastic polyps and fundus glandular polyps, 178 were male and 215 were female. The ratio of male to female was 1:1.2, aged 28-89 years. With the increase of age, the incidence of gastric polyps was higher, but the distribution of different age groups was not statistically significant (P>0.05). There were significant differences in the size of hypertrophic polyps between different parts of the stomach and glandular polyps (P<0.05). The gender distribution of the two gastric polyps was statistically significant (P<0.05). The H. pylori infection rate of hyperplastic polyps was higher than that of gastric fundus polyps (P<0.05), while the gastric fundus polyp proton pump inhibitors were higher than gastric hyperplastic polyps (P<0.05). Conclusion: Hyperplastic polyps are associated with Helicobacter pylori infection, and gastric fundus polyps are associated with the use of proton pump inhibitors. The analysis of the clinical and endoscopic features of gastric fundus polypoids and gastric hyperplastic polyps contributes to the preliminary judgment of the nature of gastric polyps by gastroscopy and improves the accuracy of diagnosis.