前部缺血性视神经病变患者图形视觉诱发电位与视功能改变的关系及其临床意义

目的:探究前部缺血性视神经病变(AION)患者图形视觉诱发电位(P-VEP)检查结果与预后间的关系。方法:选择2016年12月-2019年12月于我院就诊并确诊的AION患者作为研究对象,入院后接受综合治疗,治疗后评估患者的视功能,评价患者的治疗效果,采用相关性分析探究患者入院后P-VEP检查结果与经治疗后患者视功能改善值间的相关性。结果:研究组15'棋盘格和60'棋盘格P100波潜伏时均高于对照组,P100波振幅均低于对照组,差异均具有统计学意义(P0.05)。治疗后3个月AION患者最佳矫正视力和视野平均敏感度(MS)高于治疗前,视野平均缺失值(MD)低于治疗前,差异均具有统计学意义(P0.05)。AION患者治疗前后视力差值与15'棋盘格P100波振幅呈正相关,视野MD差值和视野MS差值与P-VEP四项反应值不具有相关性。结论:P-VEP检查结果 15'棋盘格P100波振幅与患者视力改善差值间存在显著的正相关性,可提示患者视功能恢复程度及预后。

The Relationship between P-VEP and Visual Function in Patients with Anterior Ischemic Optic Neuropathy and Its Clinical Significance

ABSTRACT Objective: To explore the relationship between pattern visual evoked potential (P-VEP )and prognosis in patients with anterior ischemic optic neuropathy (AION). Methods: From December 2016 to December 2019, AION patients who were diagnosed in our hospital were selected as the research objects. After admission, they received comprehensive treatment. After treatment, the visual function of the patients was evaluated, and the treatment effect of the patients was evaluated. The correlation analysis was used to explore the correlation between the P-VEP examination results and the improvement of visual function of the patients after treatment. Results: The latency time of P100 wave in 15 ''checker and 60''checker in the research Group was higher than that in the control group, and the amplitude of P100 wave was lower than that in the control group, the difference was statistically significant (P<0.05). 3 months after treatment, the best corrected visual acuity and the mean sensitivity(MS) of visual field of AION patients were higher than that before treatment, and the mean deletion(MD) of visual field was lower than that before treatment, the difference was statistically significant (P<0.05). There was a positive correlation between the visual acuity difference of AION patients before and after treatment and the P100 wave amplitude of 15 ''checker. There was no correlation between the MD difference of visual field and the MS difference of visual field and the four response values of P-VEP. Conclusion: The results of P-VEP showed that there was a significant positive correlation between the amplitude of 15 ''checker P100 wave and the difference of vision improvement, which could indicate the degree of visual function recovery and prognosis.