不同粘度骨水泥椎体成形术对骨质疏松椎体压缩性骨折的临床疗效及生活质量的影响

目的:比较不同粘度骨水泥椎体成形术(PVP)治疗骨质疏松椎体压缩性骨折(OVCF)的临床疗效及生活质量的影响。方法:回顾性分析于2016年8月至2018年2月期间我院收治的104例OVCF患者的临床资料。将患者按数字表法分为对照组(n=52)和研究组(n=52),两组患者均给予PVP治疗,对照组选用低粘度骨水泥,研究组选用高粘度骨水泥。比较两组患者术前、术后1周、术后1个月、术后3个月、术后6个月及术后12个月的Oswestry功能障碍指数(ODI)评分、疼痛视觉模拟量表(VAS)评分、健康状况调查问卷(SF-36)评分以及Cobb角,记录两组并发症发生情况。结果:研究组患者手术时间长于对照组(P<0.05),而两组患者骨水泥注入量、住院时间比较差异无统计学意义(P>0.05)。两组患者术后1周、1个月、3个月、6个月、12个月ODI评分、VAS评分、Cobb角均较术前降低(P<0.05);两组患者术后1个月、3个月、6个月、12个月ODI评分、VAS评分、Cobb角均较术后1周降低(P<0.05);研究组术后1周、1个月、3个月、6个月、12个月ODI评分、VAS评分、Cobb角低于对照组(P<0.05)。两组患者术后1周、1个月、3个月、6个月、12个月SF-36评分均升高,且研究组高于对照组(P<0.05)。两组并发症发生率比较无统计学差异(P>0.05)。结论:高粘度骨水泥应用于PVP治疗OVCF患者疗效确切,可有效减轻患者疼痛状况,改善生活质量,促进患者恢复。

Different Viscosities of Bone Cement Vertebroplasty on Clinical Efficacy of Osteoporotic Vertebral Compression Fractures and Its Effect of Quality of Life

ABSTRACT Objective: To compare the clinical efficacy of different viscosities of bone cement vertebroplasty (PVP) in the treatment of osteoporotic vertebral compression fractures (OVCF) and its effect of quality of life. Methods: The clinical data of 104 patients with OVCF who were admitted to our hospital from August 2016 to February 2018 were retrospectively analyzed. They were divided into control group (n=52) and study group (n=52) according to the digital table method. Both groups were treated with PVP. The control group was treated with low-viscosity bone cement, and the study group was treated with high-viscosity bone cement. Oswestry dysfunction index (ODI), visual analogue pain scale (VAS), health Questionnaire(SF-36) and Cobb angle were compared between the two groups before operation, 1 week, 1 month, 3 months, 6 months and 12 months after operation. The complications were recorded in both groups. Results: The operation time of the study group was longer than that of the control group(P<0.05), but there were no significant differences in the amount of bone cement injected and hospitalization time between the two groups(P>0.05). The ODI score, VAS score and Cobb angle of 1 week, 1 month, 3 months, 6 months and 12 months after operation in both groups were lower than those before operation(P<0.05). The ODI score, VAS score and Cobb angle of 1 month, 3 months, 6 months and 12 months after operation in both groups were lower than those of 1 week after operation(P<0.05). The ODI score, VAS score and Cobb angle of 1 week, 1 month, 3 months, 6 months, 12 months after operation in the study group were lower than those of the control group(P<0.05). The SF-36 scores of the two groups increased at 1 week, 1 month, 3 months, 6 months and 12 months after operation, and the SF-36 scores of the study group were higher than those of the control group(P<0.05). There was no significant difference in the incidence of complications between the two groups(P>0.05). Conclusion: The application of high viscosity bone cement in the treatment of OVCF patients with PVP has a definite effect, which can effectively relieve the pain, and it can improve the quality of life, and promote the recovery of patients.