Stretch induces granule exocytosis in toad urinary bladder |
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| Affiliation: | 1. Department of Gynecology and Obstetrics, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China;2. State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200240, China;1. Department of Electrical and Computer Engineering, University of Massachusetts, Amherst, MA 01003, USA;2. Department of Mechanical and Industrial Engineering, University of Massachusetts, Amherst, MA 01003, USA;1. Institut de Génétique et de Biologie Moléculaire et Cellulaire, 67404 Illkirch, France;2. Centre National de la Recherche Scientifique, UMR7104, 67404 Illkirch, France;3. INSERM, U964, 67404 Illkirch, France;4. Université de Strasbourg, 67404 Illkirch, France;5. Biozentrum, University of Basel, Klingelbergstrasse 70, 4056 Basel, Switzerland |
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| Abstract: | Evidence from thin sections and freeze-fracture is presented showing that stretch induces a burst of exocytosis in granular cells of the toad urinary bladder epithelium. Since the role of granule exocytosis in hormonally-induced permeability changes in this tissue has not yet been clarified, we propose that the stretch factor is an important parameter to consider and standardise in future physiological and morpho-functional studies using this model transporting system. |
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