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Staging in bipolar disorder: from theoretical framework to clinical utility
Authors:Michael Berk  Robert Post  Aswin Ratheesh  Emma Gliddon  Ajeet Singh  Eduard Vieta  Andre F. Carvalho  Melanie M. Ashton  Lesley Berk  Susan M. Cotton  Patrick D. McGorry  Brisa S. Fernandes  Lakshmi N. Yatham  Seetal Dodd
Affiliation:1. IMPACT Strategic Research Centre, School of Medicine, Deakin University, Geelong, Australia;2. Department of Psychiatry, University of Melbourne, Melbourne, Australia;3. Orygen, the National Centre of Excellence in Youth Mental Health, Parkville, Australia;4. Centre for Youth Mental Health, University of Melbourne, Melbourne, Australia;5. Florey Institute for Neuroscience and Mental Health, Melbourne, Australia;6. Department of Psychiatry and Behavioral Sciences, George Washington University School of Medicine and Health Sciences, Washington, DC, USA;7. Bipolar Disorders Program, Department of Psychiatry and Psychology, Institute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain;8. Translational Psychiatry Research Group and Department of Clinical Medicine, Faculty of Medicine, Federal University of Ceará, Fortaleza, Brazil;9. Institute for Clinical Research and Education in Medicine, Padua, Italy;10. Department of Psychiatry, University of British Columbia, Vancouver, Canada
Abstract:
Keywords:Bipolar disorder  clinical staging  early intervention  neuroprogression  neuroprotection  cognitive functioning  biological markers  kindling  treatment outcome  lithium  transdiagnostic framework
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