A Review Molecular Typing Methods for <Emphasis Type="Italic">Aspergillus flavus</Emphasis> Isolates |
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Authors: | Inès Hadrich Fattouma Makni Sourour Neji Fatma Cheikhrouhou Hayet Sellami Ali Ayadi |
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Institution: | 1.Faculté de médecine,Laboratoire de biologie moléculaire parasitaire et fongique,Sfax,Tunisie;2.Fungal and parasitic molecular biology laboratory,School of Medicine Sfax,Sfax,Tunisia |
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Abstract: | Aspergillus flavus is the second most important Aspergillus species causing human infections. The importance of this fungus increases in regions with a dry and hot climate. Small phylogenetic
studies in Aspergillus flavus indicate that the morphological species contains several genetically isolated species. Different genotyping methods have
been developed and employed in order to better understand the genetic and epidemiological relationships between environmental
and clinical isolates. Understanding pathogen distribution and relatedness is essential for determining the epidemiology of
nosocomial infections and aiding in the design of rational pathogen control methods. Typing techniques can also give us a
deeper understanding of the colonization pattern in patients. Most of these studies focused on Aspergillus fumigatus because it is medically the most isolated species. To date, there has not been any publication exclusively reviewing the
molecular typing techniques for Aspergillus flavus in the literature. This article reviews all these different available methods for this organism. |
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