Reactivity of carboxyl groups in modified proteins |
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Authors: | Frater R |
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Affiliation: | Division of Protein Chemistry, CSIRO, Parkville (Melbourne), 3052, Victoria, Australia |
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Abstract: | The reactivities of carboxyl groups to carbodiimides in non-reduced, S-carboxymethyl, and S-cyanoethyl proteins have been compared. When disulphide bonds are split, a decrease in reactivity was found, relatively minor in the S-carboxymethyl derivative and almost complete loss of reactivities in the S-cyanoethyl derivative. |
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