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An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans
Authors:Adil Mardinoglu  Hao Wu  Elias Bjornson  Cheng Zhang  Antti Hakkarainen  Sari M Räsänen  Sunjae Lee  Rosellina M Mancina  Mattias Bergentall  Kirsi H Pietiläinen  Sanni Söderlund  Niina Matikainen  Marcus Ståhlman  Per-Olof Bergh  Martin Adiels  Brian D Piening  Marit Granér  Nina Lundbom  Jan Borén
Institution:1. Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden;2. Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden;3. Department of Molecular and Clinical Medicine, University of Gothenburg, and Sahlgrenska University Hospital, Gothenburg, Sweden;4. HUS Medical Imaging Center, Radiology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland;5. Research Programs Unit, Diabetes and Obesity, University of Helsinki and Department of Internal Medicine, Helsinki University Hospital, Helsinki, Finland;6. Endocrinology, Abdominal Center, Helsinki University Hospital, Helsinki, Finland;7. Department of Genetics, Stanford University, Stanford, CA 94305, USA
Abstract:
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  • Keywords:NAFLD  inflammation  carbohydrate-restricted diet  multi-omics  β-oxidation  FGF21  microbiome  Streptococcus  folate  PPAR-α
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