PGI2: A potential mediator of inflammation |
| |
| Authors: | A.W. Ford-Hutchinson J.R. Walker E.M. Davidson M.J.H. Smith |
| |
| Affiliation: | Biochemical Pharmacology Research Unit, Department of Chemical Pathology, King''s College Hospital Medical School, Denmark Hill, London, SE5 8RX, England |
| |
| Abstract: | PGI2, but not its metabolite 6oxoPGF1α, is equivalent in potency to PGE1 as a potentiator of carrageenan, histamine and bradykinin-induced rat paw oedemas. PGI2 must, therefore, be considered as a potential mediator of inflammatory processes. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
