Cross resistance between oxytetracycline and oxolinic acid in Aeromonas salmonicida associated with alterations in outer membrane proteins |
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| Authors: | A.C. Barnes C.S. Lewin T.S. Hastings S.G.B. Amyes |
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| Affiliation: | Department of Bacteriology, University of Edinburgh, Medical School, U.K. |
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| Abstract: | Oxytetracycline resistant mutants of Aeromonas salmonicida isolated from mutation frequency experiments showed decreased susceptibility to oxolinic acid. Outer membrane preparations of these resistant mutant strains revealed a major protein, with a molecular mass of approximately 37 kDa, which was not present in significant quantities in the parent strain. |
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| Keywords: | Oxytetracycline resistant mutant Aeromonas salmonicida |
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