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Foxl2 gene and the development of the ovary: a story about goat, mouse, fish and woman |
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| Authors: | Baron Daniel Batista Frank Chaffaux Stéphane Cocquet Julie Cotinot Corinne Cribiu Edmond De Baere Elfride De Baeree Elfride Guiguen Yann Jaubert Francis Pailhoux Eric Pannetier Maëlle Vaiman Daniel Vigier Bernard Veitia Reiner Fellous Marc |
| Affiliation: | Equipe Sexualité et Reproduction, INRA-SCRIBE, Département PHASE, Campus de Beaulieu, 35042 Rennes Cedex, France. ellous@cochin.inserm.fr |
| Abstract: | In this review, we describe recent results concerning the genetics of sex determination in mammals. Particularly, we developed the study of the FOXL2 gene and its implication in genetic anomalies in goats (PIS mutation) and humans (BPES). We present the expression of FOXL2 in the ovaries of different species. |
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