Lipoprotein lipase activity in the flight muscle of Locusta migratoria and its specificity for haemolymph lipoproteins |
| |
| Institution: | 1. Department of Hematology, Oncology, and Stem Cell Transplantation, Children''s Healthcare of Atlanta and Emory University, Atlanta, GA, USA;2. Department of Biostatistics, St Jude Children''s Research Hospital, Memphis, TN, USA;3. Department of Oncology, St Jude Children''s Research Hospital, Memphis, TN, USA;4. Department of Pharmaceutical Science, St Jude Children''s Research Hospital, Memphis, TN, USA;5. Department of Diagnostic Imaging, St Jude Children''s Research Hospital, Memphis, TN, USA;6. Department of Radiology, Boston Children''s Hospital, Boston, MA, USA;7. Department of Pathology, Brigham and Women''s Hospital, Harvard Medical School, Boston, MA, USA;8. Center for Cancer and Blood Disorders, University of California, San Francisco, San Francisco, CA, USA;9. Department of Radiology, University of California, San Francisco, San Francisco, CA, USA;10. Department of Neurology, Children''s National Medical Center, Washington, DC, USA;11. Department of Haematology and Oncology, Children''s National Medical Center, Washington, DC, USA;12. Department of Radiology, Children''s National Medical Center, Washington, DC, USA;13. Department of Haematology, Oncology, Neuro-Oncology, and Stem Cell Transplantation, Ann and Robert H Lurie Children''s Hospital of Chicago, Chicago, IL, USA;14. Department of Radiology, Ann and Robert H Lurie Children''s Hospital of Chicago, Chicago, IL, USA;15. Department of Neurosurgery, Children''s Hospital of Pittsburgh, Pittsburgh, PA, USA;p. Department of Hematology and Oncology, Children''s Hospital of Pittsburgh, Pittsburgh, PA, USA;q. Department of Radiology, Children''s Hospital of Pittsburgh, Pittsburgh, PA, USA;r. Department of Neurology, Stanford University Medical Center, Palo Alto, CA, USA;s. Department of Hematology and Oncology, Children''s Hospital Los Angeles, Los Angeles, CA, USA;t. Department of Radiology, Children''s Hospital Los Angeles, Los Angeles, CA, USA;u. Department of Hematology and Oncology, Texas Children''s Hospital, Houston, TX, USA;v. Department of Hematology and Oncology, Duke University School of Medicine, Durham, NC, USA;w. Department of Radiology, Duke University School of Medicine, Durham, NC, USA;x. Department of Pediatric Glioma Research Group, Hopp Children''s Cancer Center Heidelberg (KiTZ) and German Cancer Research Center (DKFZ), Heidelberg, Germany;y. Department of Pediatric Neuro-Oncology, Hopp Children''s Cancer Center Heidelberg (KiTZ) and German Cancer Research Center (DKFZ), Heidelberg, Germany;z. Department of Radiology, Nationwide Children''s Hospital, Columbus, OH, USA;11. Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA;12. Department of Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA;13. Department of Pediatric Oncology, The Children''s Hospital of Philadelphia, Philadelphia, PA, USA;14. Investigational Drug Branch, National Cancer Institute and Cancer Therapy Evaluation Program, Bethesda, MD, USA;15. Clinical Investigation Branch, National Cancer Institute and Cancer Therapy Evaluation Program, Bethesda, MD, USA;16. Department of Haematology and Oncology, Cincinnati Children''s Hospital, Cincinnati, OH, USA;1. Department of Obstetrics and Gynecology, Human Reproduction Unit, Cruces University Hospital, Basque Country University, Bizkaia, Bilbao, Spain;2. BioCruces Health Research Institute, Spain;3. Instituto Valenciano de Infertilidad, IVI Bilbao, IVIRMA, Bilbao, Spain;4. EMD Serono Research & Development Institute, Inc., Billerica, USA;5. Pharma Value Consulting, Switzerland;6. Merck Healthcare, Merck KGaA, Darmstadt, Germany;7. Scientific Centre for Endometriosis, University Hospitals of Saarland, Saarbrücken, Germany;8. Department of Gynecology, Jena-University Hospital-Friedrich Schiller University, Jena, Germany;9. Cha University, Fertility Centre, Bundang Medical Centre, Seongnam, Gyeonggi-do, South Korea;10. Seoul Maria Fertility Hospital, Seoul, South Korea;11. Department of Obstetrics, Gynecology and Reproductive Medicine, La Paz University Hospital, Madrid, Spain;12. Department of Reproductive Medicine, Ruber Internacional Hospital, Madrid, Spain;13. Department of Development and Regeneration, Laboratory of Endometrium, Endometriosis & Reproductive Medicine, KU Leuven, Leuven, Belgium;14. Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University Medical School, New Haven, USA;15. Department of Reproductive Medicine and Surgery, Manchester Academic Health Sciences Centre, Manchester, UK;1. Aly Lab, Beykoz Institute of Life Sciences and Biotechnology, Bezmialem Vakif University, Istanbul 34820, Turkey;2. Department of Biotechnology, Institute of Health Sciences, Bezmialem Vakif University, Istanbul, Turkey;3. School of Science and Engineering, Al Akhawayn University, Ifrane 53000, Morocco;1. Department of Pharmacy, Henan Medical College, Zhengzhou, 451191 Henan, PR China;2. Henan Key Laboratory of Polyoxometalate Chemistry, College of Chemistry and Chemical Engineering, Henan University, Kaifeng, Henan 475004, PR China;1. Department of Plant Protection Biology, Swedish University of Agricultural Sciences, Box 102, SE-230 53 Alnarp, Sweden;2. Hushållningssällskapet Skåne, Box 9084, 291 09 Kristianstad, Sweden;3. Department of Chemistry, Mkwawa University College of Education, University of Dar es Salaam, P.O. Box 2513, Iringa, Tanzania;4. IAEA Laboratories, A-2444 Seibersdorf, Austria;1. Department of Energy Systems Research and Department of Materials Science and Engineering, Ajou University, Suwon 16499, South Korea;2. Samsung Advanced Institute of Technology, Suwon 16674, South Korea;3. School of Advanced Materials Science and Engineering, Sungkyunkwan University, Suwon 16419, South Korea;4. National Graphene Institute, University of Manchester, Manchester M13 9PL, United Kingdom;5. Center for Nanomaterials and Chemical Reactions, Institute for Basic Science (IBS), Daejeon 34141, South Korea;6. Ames Laboratory, Ames, IA 50011, United States |
| |
| Abstract: | Lipoprotein lipase activity in flight muscle homogenates of Locusta migratoria was measured, using natural radiolabelled lipoproteins as substrates. The flight specific lipoprotein A+ (or low density lipophorin) stimulated lipoprotein lipase activity several-fold compared to the resting lipoprotein Ay (or high density lipophorin). However, with the high mol. wt lipoprotein fraction OAKH as a substrate, lipase activity was even doubled compared to lipoprotein A+. Lipase activity was not increased in flight muscle homogenates of insects which had flown. Neither adipokinetic hormone, nor octopamine had any direct effect on lipoprotein lipase activity. Aspects of hormonal regulation and apoprotein activation of the locust flight muscle lipoprotein lipase are discussed and compared with the model for vertebrate lipoprotein lipase. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
