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Zeaxanthin and menaquinone-7 biosynthesis in Sphingobacterium multivorum via the methylerythritol phosphate pathway
Authors:Surya Rosa-Putra  réa Hemmerlin  Jean Epperson  Thomas J Bach  Luis H Guerra  Michel Rohmer
Institution:Université Louis Pasteur/CNRS, Institut Le Bel, Strasbourg Cedex, France.
Abstract:Feeding of 1-(13)C]glucose, U-(13)C(6)]glucose, 3-(13)C]alanine and 1-(13)C]acetate to Sphingobacterium multivorum showed that this bacterium utilizes the methylerythritol phosphate pathway for the biosynthesis of menaquinone-7 and zeaxanthin, a carotenoid of industrial importance. Differential incorporation of the labeled precursors gave some insight into the preferred carbon sources involved in isoprenoid biosynthesis.
Keywords:Carotenoid  Deoxyxylulose  Isopentenyl diphosphate  Isoprenoid  Menaquinone  Mevalonate  Methylerythritol              Sphingobacterium            Terpenoid  Zeaxanthin
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