Université Louis Pasteur/CNRS, Institut Le Bel, Strasbourg Cedex, France.
Abstract:
Feeding of 1-(13)C]glucose, U-(13)C(6)]glucose, 3-(13)C]alanine and 1-(13)C]acetate to Sphingobacterium multivorum showed that this bacterium utilizes the methylerythritol phosphate pathway for the biosynthesis of menaquinone-7 and zeaxanthin, a carotenoid of industrial importance. Differential incorporation of the labeled precursors gave some insight into the preferred carbon sources involved in isoprenoid biosynthesis.