A comparison of menotropin, highly-purified menotropin and follitropin alfa in cycles of intracytoplasmic sperm injection |
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Authors: | Sandro C Esteves Joan C Schertz Sidney Verza Jr Danielle T Schneider Silval FC Zabaglia |
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Affiliation: | 1. ANDROFERT, Centro de Referência para Reprodu??o Masculina, Av. Dr. Heitor Penteado, 1464, 13075-460, Campinas, S?o Paulo, Brazil 2. EMD Serono, Merck KGaA, Rockland, MA, USA
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Abstract: | Background Over the last several decades, as a result of an evolution in manufacturing processes, a marked development has been made in the field of gonadotropins for ovarian stimulation. Initially, therapeutic gonadotropins were produced from a simple process of urine extraction and purification; now they are produced via a complex system involving recombinant technology, which yields gonadotropins with high levels of purity, quality, and consistency. |
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