LKB1 kinase: master and commander of metabolism and polarity |
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| Authors: | Spicer James Ashworth Alan |
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| Affiliation: | Department of Medical Oncology, Guy's Hospital, St Thomas's Street, London SE1 9RT, UK. |
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| Abstract: | LKB1, the product of a tumour suppressor gene, is a serine/threonine kinase that coordinates disparate cellular processes. Recent data have revealed novel functions for LKB1, providing new insight into the regulation of cell polarity and energy-generating metabolism. |
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