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Structural mechanism for the fine-tuning of CcpA function by the small molecule effectors glucose 6-phosphate and fructose 1,6-bisphosphate
Authors:Schumacher Maria A  Seidel Gerald  Hillen Wolfgang  Brennan Richard G
Affiliation:Department of Biochemistry and Molecular Biology, Unit 1000, University of Texas, MD Anderson Cancer Center University, 1515 Holcombe Boulevard, Houston, TX 77030, USA. maschuma@mdanderson.org
Abstract:
Keywords:CCR, carbon catabolite regulation   CcpA, carbon catabolite activator protein A   HPr, histidine-containing protein   Crh, catabolite repression HPr   PTS, phosphoenolpyruvate:sugar phosphotransferase system   G6P, glucose 6-phosphate   HTH, helix-turn-helix   FBP, fructose 1,6-bisphosphate   MR, molecular replacement   RMSD, root-mean-square deviation
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