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Human 2-Oxoglutarate Dehydrogenase and 2-Oxoadipate Dehydrogenase Both Generate Superoxide/H2O2 in a Side Reaction and Each Could Contribute to Oxidative Stress in Mitochondria |
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| Authors: | Jordan Frank Nemeria Natalia Gerfen Gary |
| Affiliation: | 1.Department of Chemistry, Rutgers University, 73 Warren St, Newark, NJ, 07102-1811, USA ;2.Department of Physiology and Biophysics, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY, 10641-2304, USA ; |
| Abstract: | Neurochemical Research - According to recent findings, the human 2-oxoglutarate dehydrogenase complex (hOGDHc) could be an important source of the reactive oxygen species in the mitochondria and... |
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